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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

This activity guides the analysis of a published scientific figure from a study that compared the testosterone levels of Olympic-level elite athletes.

This activity explores images of planarians regenerating missing body parts, which serve as phenomena for learning about cell division and differentiation.

This activity analyzes a published scientific figure from a study that investigated the biological importance of sleep. In this study, scientists tested whether sleep plays a role in removing harmful substances from the brain.

This activity guides the analysis of a published scientific figure from a study that investigated how random mutations during cell division can contribute to cancer.

This activity explores images of chalk formations and coccolithophores, which serve as phenomena for learning about the interactions between biological and geological processes.

This activity explores an image of early embryonic cells, which serves as a phenomenon for learning about cell division and development.

This activity reinforces concepts presented in the short film The Making of a Theory. Using a map of the Malay Archipelago and information about the animals found on different islands, students discover the Wallace Line: a sharp boundary that separates distinct Asian and Australian fauna.

This activity guides students through building a conceptual model of how carbon dioxide affects Earth’s climate.

This activity supports concepts covered in the film The Day the Mesozoic Died. Students will analyze geological evidence from 10 different sites around the world to predict the location of the asteroid impact that caused the mass extinction at the end of the Cretaceous Period.