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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this activity, wildfires and how much area they burn serve as a phenomenon to guide student inquiry, which includes evaluating data and developing scientific claims.

This activity explores images of a coral bleaching event, which serve as phenomena for learning about marine ecosystems, human impacts, and climate change.

This activity explores the concepts and research presented in the short film Out of the Ashes: Dawn of the Age of Mammals, which explores how life on Earth recovered after a major asteroid impact.

This activity guides the analysis of a published scientific figure from a study that explored the evolutionary origins of parasitic beetles that mimic army ants.

This activity explores an image of tattoo ink particles inside cells, which serves as a phenomenon for learning about the structure and color of human skin.

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

This activity guides the analysis of a published scientific figure from a study that investigated how salt affects the electron transport chain.

This activity explores images of plant cells and structures, which serve as phenomena for learning about how plants respond to stimuli.

This hands-on activity allows students to analyze DNA sequences of Ebola viruses. Students use these sequences to track the virus’s spread during the 2013–2016 Ebola outbreak in West Africa.

This activity explores images of chalk formations and coccolithophores, which serve as phenomena for learning about the interactions between biological and geological processes.

In this hands-on activity, students simulate the effects of decreasing pH caused by rising levels of atmospheric carbon dioxide.