In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.
In this activity, students interpret several pedigrees of autosomal dominant and recessive conditions and consider the benefits and limitations of genetic testing.
In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
This video presents an intriguing phenomenon: two patients who carry the same genetic variation, which is known to cause sickle cell disease, have very different outcomes.
This video case study explores the approaches scientists used to identify a mutation that causes retinitis pigmentosa (RP), a progressive disease that leads to blindness.
In this activity, students engage with an example from the Serengeti ecosystem to illustrate the exchange of nutrients between plants, animals, and the environment.
This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.
This activity explores an image of tattoo ink particles inside cells, which serves as a phenomenon for learning about the structure and color of human skin.
This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.
This interactive module consists of a virtual Winogradsky column, which can be used to explore the diversity of microbes, microbial metabolic strategies, and geochemical gradients found in sediments.