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In this activity, students interpret several pedigrees of autosomal dominant and recessive conditions and consider the benefits and limitations of genetic testing.

This highly customizable activity guides students through organizing and documenting spreadsheet data during a class investigation.

This activity guides the analysis of a published scientific figure from a study that explored inbreeding depression in a small, isolated population of wolves.

In this activity, students work with authentic research data to explore the impact of poaching on African elephants.

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.

This activity guides the analysis of a published scientific figure from a study on how social status affects the expression of genes involved in immune system processes.

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

This activity analyzes a published scientific figure from a study assessing if the microbiota from a mother affects the immune systems of the developing offspring.

This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.

This multipart activity is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensics labs around the world.

In this activity, students extend the concepts covered in the short film The Biology of Skin Color through the application of models and mathematical thinking to explain how genomic variation and human ancestry can explain differences in skin color, a polygenic trait.

This activity analyzes a published scientific figure from a study of a family that has a high prevalence of Alzheimer’s disease.