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Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness.

Monkey Social Status and Immune Response

This activity guides the analysis of a published scientific figure from a study on how social status affects the expression of genes involved in immune system processes.

Activity for Genes as Medicine

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

Evolution Course

This asynchronous course is designed to deepen educators' content knowledge in evolution, especially regarding content appropriate for teaching at the high school level. 

Genes as Medicine

This film describes the scientific principles and the research efforts involved in the development of a gene therapy for a congenital form of blindness, and how a young patient benefited from this medical breakthrough.

HIV Receptors and Co-receptors

This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.

DNA Profiling Activity

This multipart activity is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensics labs around the world.

Understanding Variation in Human Skin Color

In this activity, students extend the concepts covered in the short film The Biology of Skin Color through the application of models and mathematical thinking to explain how genomic variation and human ancestry can explain differences in skin color, a polygenic trait.

Spreadsheet Tutorial 4: t-Test

In this activity, students explore different ways of calculating t-values and performing t-tests using built-in functions in Excel or Google Sheets. Students apply what they learned by plotting beak size measurements of Galapágos finches collected before and after a drought.