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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.
This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.
This activity explores images of animals with a mutation that affects coloration, which serve as phenomena for learning about skin color genetics and evolution.
This activity explores images of planarians regenerating missing body parts, which serve as phenomena for learning about cell division and differentiation.
This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.
This activity challenges students to provide their questions and ideas for experiments they could conduct to investigate the impact of releasing genetically modified mosquitoes into the wild. It accompanies the video Genetically Modified Mosquitoes.