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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this activity, wildfires and how much area they burn serve as a phenomenon to guide student inquiry, which includes evaluating data and developing scientific claims.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

This activity explores images of a coral bleaching event, which serve as phenomena for learning about marine ecosystems, human impacts, and climate change.

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

This activity guides the analysis of a published scientific figure from a study that investigated how salt affects the electron transport chain.

This activity complements the animated short video Seeing the Invisible. Students explore concepts related to relative size and scale using cards of cells and microorganisms.

This activity analyzes a published scientific figure from a study that investigated the biological importance of sleep. In this study, scientists tested whether sleep plays a role in removing harmful substances from the brain.

This activity guides the analysis of a published scientific figure from a study that investigated how random mutations during cell division can contribute to cancer.

This activity explores images of chalk formations and coccolithophores, which serve as phenomena for learning about the interactions between biological and geological processes.

In this hands-on activity, students simulate the effects of decreasing pH caused by rising levels of atmospheric carbon dioxide.

This activity analyzes a figure showing the atmospheric carbon dioxide concentration from 1958 to 2023.