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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this activity, students explore using CRISPR-Cas9 to knock out butterfly genes in order to determine their function.

In this activity, students analyze aspects of a scientific paper that investigates genes involved in the colors and patterns of butterfly wings.

In this hands-on activity, students build a paper model to explore how CRISPR-Cas9 is used to edit genes.

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.

This activity explores images of animals with a mutation that affects coloration, which serve as phenomena for learning about skin color genetics and evolution.

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

This activity explores images of the bobtail squid, which serve as phenomena for learning about symbiosis and interspecies interactions.

This video describes the case of a patient with retinitis pigmentosa (RP), a progressive disease that leads to blindness, and how physician-scientist Dr. Ed Stone approached the search for the causal mutation.

This film describes the scientific principles and the research efforts involved in the development of a gene therapy for a congenital form of blindness, and how a young patient benefited from this medical breakthrough.

This video describes how scientists silence different genes in regenerating planaria to study the process of regeneration at the molecular level.

This activity challenges students to provide their questions and ideas for experiments they could conduct to investigate the impact of releasing genetically modified mosquitoes into the wild. It accompanies the video Genetically Modified Mosquitoes.