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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

This interactive module introduces the anatomy of the immune system and walks through the timeline of a typical immune response.

This interactive module allows students and educators to build models that explain how the Earth system works. The Click & Learn can be used to show how Earth is affected by human activities and natural phenomena.

This activity explores images of the bobtail squid, which serve as phenomena for learning about symbiosis and interspecies interactions.

This activity guides the analysis of a published scientific figure from a study that investigated how random mutations during cell division can contribute to cancer.

This animation illustrates the main stages of the water cycle in Gorongosa National Park, an ecosystem that experiences both wet and dry seasons.

This activity allows students to use authentic scientific data to make claims about the threat of coral bleaching for reefs around the world.

A number of questions are embedded within the short film The Making of the Fittest: The Birth and Death of Genes, which illustrates how gene duplications and mutations have led to remarkable physiological adaptations in Antarctic fish.