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“Fixing” Gene Expression

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

Stalking the Genetic Basis of a Trait

This activity supports the film Popped Secret: The Mysterious Origin of Corn. Students analyze data on the expression of the tb1 gene to explain how variations in this gene played a role in the evolution of corn.

Central Dogma and Genetic Medicine

This interactive module uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat different genetic conditions.

Viral DNA Integration

In this hands-on activity, students model how a double-stranded DNA copy of the HIV genome is integrated into the host cell DNA.

Cell Division and Cancer Risk

This activity guides the analysis of a published scientific figure from a study that investigated how random mutations during cell division can contribute to cancer.

HIV Reverse Transcription and AZT

This activity allows students to model how the anti-HIV drug AZT (azidothymidine) interferes with the process of viral replication.

DNA Profiling Activity

This multipart activity is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensics labs around the world.

Selective Breeding in Maize

This activity guides the analysis of a published scientific figure from the world’s longest-running controlled artificial selection study, in which scientists tested whether they could use selective breeding to change the protein concentration of maize (corn).

CSI Wildlife

This interactive module allows students to use DNA profiling and related biological concepts to solve two cases of elephant poaching.

The Teosinte Hypothesis

In this activity, students further explore the short film Popped Secret: The Mysterious Origin of Corn, by working through the mathematical concepts behind George Beadle’s claim that teosinte is the wild ancestor of maize.