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“Fixing” Gene Expression

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

Central Dogma and Genetic Medicine

This interactive module uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat different genetic conditions.

Viral DNA Integration

In this hands-on activity, students model how a double-stranded DNA copy of the HIV genome is integrated into the host cell DNA.

HIV Reverse Transcription and AZT

This activity allows students to model how the anti-HIV drug AZT (azidothymidine) interferes with the process of viral replication.

DNA Profiling Activity

This multipart activity is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensics labs around the world.

CSI Wildlife

This interactive module allows students to use DNA profiling and related biological concepts to solve two cases of elephant poaching.

Amylase Copy Number and Diet

This activity guides the analysis of a published scientific figure from a study that investigated whether there is a correlation between a population’s diet and copies of a certain gene.

BCR-ABL: Protein Structure and Function

This tutorial describes the structure and function of the cancer-causing protein BCR-ABL. It also shows how drugs targeting this protein can help treat chronic myeloid leukemia (CML), a cancer of the white blood cells.

Pulse Chase Primer: The Meselson-Stahl Experiment

This activity can be used in conjunction with the short film The Double Helix. It introduces students to the classic experiment by Matthew Meselson and Franklin Stahl, which revealed that DNA replication follows the semiconservative model.

Activity for The Double Helix

This activity explores the concepts and research presented in the short film The Double Helix, which tells the story of the discovery of the molecular structure of DNA.

The Double Helix

This film tells the story of the scientists and the evidence involved in one of the most important scientific quests of the 20th century: the discovery of the structure of DNA.