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In this activity, students interpret several pedigrees of autosomal dominant and recessive conditions and consider the benefits and limitations of genetic testing.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

This activity explores content presented in the animated video Solving Crimes with the Necrobiome, which describes the microbial changes associated with decomposing corpses.

This video case study explores the approaches scientists used to identify a mutation that causes retinitis pigmentosa (RP), a progressive disease that leads to blindness.

This activity explores images of anole lizards subjected to strong winds, which serve as phenomena for learning about natural selection and the impacts of extreme climate events.

This activity guides the analysis of a published scientific figure from a study that investigated how anole lizards may adapt to extremely cold temperatures.

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.

This interactive module allows students and educators to build models that explain how the Earth system works. The Click & Learn can be used to show how Earth is affected by human activities and natural phenomena.

This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.

This interactive module consists of a virtual Winogradsky column, which can be used to explore the diversity of microbes, microbial metabolic strategies, and geochemical gradients found in sediments.

This interactive module explores how CRISPR-Cas9 technology works and the many ways in which scientists are using it in their research.

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”