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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this activity, students interpret several pedigrees of autosomal dominant and recessive conditions and consider the benefits and limitations of genetic testing.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

In this inquiry-based activity, students engage in science practices to figure out ways environmental factors drive the natural selection and adaptation of Galápagos finches.

This activity explores the concepts and research presented in the short film Out of the Ashes: Dawn of the Age of Mammals, which explores how life on Earth recovered after a major asteroid impact.

This activity explores images of stickleback fish, some with spines and some without spines, which serve as phenomena for learning about gene regulation and natural selection.

This activity explores an image of fossil footprints at Laetoli, which serves as a phenomenon for learning about fossil evidence and human evolution.

This activity explores images of anole lizards subjected to strong winds, which serve as phenomena for learning about natural selection and the impacts of extreme climate events.

This activity guides the analysis of a published scientific figure from a study that investigated how anole lizards may adapt to extremely cold temperatures.

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.

This activity explores an image of tattoo ink particles inside cells, which serves as a phenomenon for learning about the structure and color of human skin.

This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.