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Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness.

Library of spider silk could hold secrets for new materials

A lab at the American Museum of Natural History is uncovering the genes behind each type of spider silk to create a sort of “silk library.” It’s part of an effort to learn how spiders make so many kinds of silk and what allows each kind to behave differently.

Skin Color and Human Evolution

This activity guides the analysis of a published scientific figure from a study that investigated genetic factors contributing to skin color differences, particularly within African populations.

Doctors use HIV in gene therapy to fix ‘bubble boy’ disease

They were born without a working germ-fighting system, every infection a threat to their lives. Now eight babies with “bubble boy disease” have had it fixed by a gene therapy made from one of the immune system’s worst enemies — HIV, the virus that causes AIDS.

Sodium Channel Evolution in Electric Fish

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

Chinese researcher claims first gene-edited babies

A Chinese researcher claims that he helped make the world’s first genetically edited babies — twin girls born this month whose DNA he said he altered with a powerful new tool capable of rewriting the very blueprint of life. If true, it would be a profound leap of science and ethics. A U.S.