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Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness.

Skin Color and Human Evolution

This activity guides the analysis of a published scientific figure from a study that investigated genetic factors contributing to skin color differences, particularly within African populations.

Doctors use HIV in gene therapy to fix ‘bubble boy’ disease

They were born without a working germ-fighting system, every infection a threat to their lives. Now eight babies with “bubble boy disease” have had it fixed by a gene therapy made from one of the immune system’s worst enemies — HIV, the virus that causes AIDS.

Sodium Channel Evolution in Electric Fish

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

Testosterone Levels in Elite Athletes

This activity guides the analysis of a published scientific figure from a study that compared the testosterone levels of Olympic-level elite athletes.