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Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness.

Coloration in Vertebrates

This activity explores images of animals with a mutation that affects coloration, which serve as phenomena for learning about skin color genetics and evolution.

Activity for Genes as Medicine

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

Tracking Genetically Modified Mosquitoes

This activity challenges students to provide their questions and ideas for experiments they could conduct to investigate the impact of releasing genetically modified mosquitoes into the wild. It accompanies the video Genetically Modified Mosquitoes.

DNA Profiling Activity

This multipart activity is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensics labs around the world.

Ebola: Disease Detectives

This hands-on activity allows students to analyze DNA sequences of Ebola viruses. Students use these sequences to track the virus’s spread during the 2013–2016 Ebola outbreak in West Africa.

How Do Fibers Form?

In this activity, students construct models of sickle cell hemoglobin fibers inside red blood cells to illustrate how changes in the structure of a protein can affect cell shape, as described in the short film The Making of the Fittest: Natural Selection in Humans.