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Evolution Course

This asynchronous course is designed to deepen educators' content knowledge in evolution, especially regarding content appropriate for teaching at the high school level. 

Genetic Mutations and Disease

This interactive module explores how mutations arise in germline and somatic cells. It also shows how these mutations can lead to genetic conditions, such as cystic fibrosis and cancer.

The Eukaryotic Cell Cycle and Cancer

This interactive module explores the phases, checkpoints, and protein regulators of the cell cycle. The module also shows how mutations in genes that encode cell cycle regulators can lead to the development of cancer.

BCR-ABL: Protein Structure and Function

This tutorial describes the structure and function of the cancer-causing protein BCR-ABL. It also shows how drugs targeting this protein can help treat chronic myeloid leukemia (CML), a cancer of the white blood cells.

BCR-ABL

This model shows the structure of the protein BCR-ABL, which causes a type of cancer called chronic myeloid leukemia.

Gleevec-Resistant BCR-ABL

This model shows a mutated form of the cancer-causing protein BCR-ABL that is resistant to the drug Gleevec.

Adenosine Triphosphate (ATP)

This model shows the structure of ATP, a molecule that provides energy for cellular processes, including protein phosphorylation.

Paleoclimate: A History of Change

This interactive module examines Earth’s past and present climate, highlighting the effects of two important factors: solar radiation and the composition of the atmosphere.

Geological History of Oxygen

This interactive module explores how the changes in oxygen levels throughout Earth’s history have impacted the planet’s environment and types of life.