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Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness.

Diving Adaptations in Sea Nomads

This activity guides the analysis of a published scientific figure from a study that investigated physiological and genetic adaptations in the Bajau, a group of people who traditionally do freediving.

Coloration in Vertebrates

This activity explores images of animals with a mutation that affects coloration, which serve as phenomena for learning about skin color genetics and evolution.

How Science Works

This interactive module allows students and educators to document, annotate, and reflect upon scientific research processes.

Activity for Genes as Medicine

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

The Search for a Mutated Gene

This video describes the case of a patient with retinitis pigmentosa (RP), a progressive disease that leads to blindness, and how physician-scientist Dr. Ed Stone approached the search for the causal mutation.