In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.
In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
This video case study explores the approaches scientists used to identify a mutation that causes retinitis pigmentosa (RP), a progressive disease that leads to blindness.
This activity guides the analysis of a published scientific figure from a study that explored the evolutionary origins of parasitic beetles that mimic army ants.
This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.
This activity explores images of animals with a mutation that affects coloration, which serve as phenomena for learning about skin color genetics and evolution.
This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.
This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.