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Skin Color and Human Evolution

This activity guides the analysis of a published scientific figure from a study that investigated genetic factors contributing to skin color differences, particularly within African populations.

Sodium Channel Evolution in Electric Fish

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

Pelvic Evolution in Sticklebacks

This activity guides the analysis of a published scientific figure from a study that used SNP genotyping to identify the mutations that result in morphological differences in stickleback fish.

“Fixing” Gene Expression

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

Monkey Social Status and Immune Response

This activity guides the analysis of a published scientific figure from a study on how social status affects the expression of genes involved in immune system processes.

The Search for a Mutated Gene

This video describes the case of a patient with retinitis pigmentosa (RP), a progressive disease that leads to blindness, and how physician-scientist Dr. Ed Stone approached the search for the causal mutation.

Stalking the Genetic Basis of a Trait

This activity supports the film Popped Secret: The Mysterious Origin of Corn. Students analyze data on the expression of the tb1 gene to explain how variations in this gene played a role in the evolution of corn.

Central Dogma and Genetic Medicine

This interactive module uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat different genetic conditions.

HIV Receptors and Co-receptors

This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.