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This film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell disease.

This video follows biologist Elinor Karlsson, who studies dogs to find genes associated with traits, including certain diseases.

This video presents an intriguing phenomenon: two patients who carry the same genetic variation, which is known to cause sickle cell disease, have very different outcomes.

This video case study explores the approaches scientists used to identify a mutation that causes retinitis pigmentosa (RP), a progressive disease that leads to blindness.

This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop treatments for the disease.

This interactive module explores how CRISPR-Cas9 technology works and the many ways in which scientists are using it in their research.

This video describes the case of a patient with retinitis pigmentosa (RP), a progressive disease that leads to blindness, and how physician-scientist Dr. Ed Stone approached the search for the causal mutation.

This film describes the scientific principles and the research efforts involved in the development of a gene therapy for a congenital form of blindness, and how a young patient benefited from this medical breakthrough.

This interactive module uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat different genetic conditions.

This interactive module explores how mutations arise in germline and somatic cells. It also shows how these mutations can lead to genetic conditions, such as cystic fibrosis and cancer.

This interactive module allows students to examine evidence from brain anatomy, tissue histology, and genetic studies to identify possible targets for the treatment of Alzheimer’s disease.

This interactive module explores the phases, checkpoints, and protein regulators of the cell cycle. The module also shows how mutations in genes that encode cell cycle regulators can lead to the development of cancer.