1 - 12 of 116 results

Sickle Cell: Natural Selection in Humans

This film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell disease.

Genetics
Evolution
Short Films
High School — General
High School — AP/IB
College

Why Can Some Digest Dairy and Others Cannot?

In this activity, students investigate the phenomenon of lactase persistence by making sense of a series of data sets.

Biochemistry & Molecular Biology
Genetics
Evolution
Lessons
High School — General
High School — AP/IB
College

How Do Some Cells Affect Mouse Color?

In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

Cell Biology
Genetics
Lessons
High School — General
High School — AP/IB
College

Analyzing Pedigrees

In this activity, students interpret several pedigrees of autosomal dominant and recessive conditions and consider the benefits and limitations of genetic testing.

Science Practices
Genetics
Lessons
High School — AP/IB
College

Inbreeding in Island Wolves

This activity guides the analysis of a published scientific figure from a study that explored inbreeding depression in a small, isolated population of wolves.

Genetics
Evolution
Environmental Science
Science Practices
Data Points
High School — General
High School — AP/IB
College

From Dog DNA to Human Diseases

This video follows biologist Elinor Karlsson, who studies dogs to find genes associated with traits, including certain diseases.

Genetics
Evolution
Scientists at Work
High School — General
High School — AP/IB
College

Why Do Some People with the Sickle Cell Genotype Not Have Symptoms?

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

Biochemistry & Molecular Biology
Genetics
Card Activities
High School — General
High School — AP/IB
College

A Genetic Treatment for Sickle Cell Disease

This video presents an intriguing phenomenon: two patients who carry the same genetic variation, which is known to cause sickle cell disease, have very different outcomes.

Genetics
Scientists at Work
High School — General
High School — AP/IB
College

What Causes Different Fur Colors?

In this inquiry-based activity, students investigate the phenomenon of fur colors in rock pocket mice to connect genotypes to phenotypes and molecular genetics to evolution.

Genetics
Evolution
Lessons
High School — General
High School — AP/IB

Stickleback Spines

This activity explores images of stickleback fish, some with spines and some without spines, which serve as phenomena for learning about gene regulation and natural selection.

Genetics
Evolution
Phenomenal Images
High School — General
High School — AP/IB
College

Interactive Case Study for The Search for a Mutated Gene

This video case study explores the approaches scientists used to identify a mutation that causes retinitis pigmentosa (RP), a progressive disease that leads to blindness.

Biochemistry & Molecular Biology
Genetics
Science Practices
Interactive Videos
High School — AP/IB
College

Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.

Biochemistry & Molecular Biology
Genetics
Lessons
High School — General
High School — AP/IB
College