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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this Click & Learn, students explore factors that contribute to patterns seen in the Keeling Curve: a continuous record of atmospheric CO₂ starting in 1958.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

This interactive module introduces the anatomy of the immune system and walks through the timeline of a typical immune response.

This activity guides the analysis of a published scientific figure from a study on how social status affects the expression of genes involved in immune system processes.

This activity analyzes a published scientific figure from a study assessing if the microbiota from a mother affects the immune systems of the developing offspring.

This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.

This activity guides the analysis of a published scientific figure from a study that investigated how random mutations during cell division can contribute to cancer.

This activity analyzes a figure showing the atmospheric carbon dioxide concentration from 1958 to 2023.

A number of questions are embedded within the short film The Making of the Fittest: The Birth and Death of Genes, which illustrates how gene duplications and mutations have led to remarkable physiological adaptations in Antarctic fish.

This activity guides students through building a conceptual model of how carbon dioxide affects Earth’s climate.

This interactive module examines Earth’s past and present climate, highlighting the effects of two important factors: solar radiation and the composition of the atmosphere.