1 - 12 of 33 results
Cystic Fibrosis Mechanism and Treatment

This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop treatments for the disease.

The Search for a Mutated Gene

This video describes the case of a patient with retinitis pigmentosa (RP), a progressive disease that leads to blindness, and how physician-scientist Dr. Ed Stone approached the search for the causal mutation.

Genes as Medicine

This film describes the scientific principles and the research efforts involved in the development of a gene therapy for a congenital form of blindness, and how a young patient benefited from this medical breakthrough.

Central Dogma and Genetic Medicine

This interactive module uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat different genetic conditions.

Genetic Mutations and Disease

This interactive module explores how mutations arise in germline and somatic cells. It also shows how these mutations can lead to genetic conditions, such as cystic fibrosis and cancer.

CSI Wildlife

This interactive module allows students to use DNA profiling and related biological concepts to solve two cases of elephant poaching.

Metabarcoding

This video describes the technology of metabarcoding, which allows scientists to determine herbivore diets based on the sequences of plant DNA extracted from animal dung.

The Eukaryotic Cell Cycle and Cancer

This interactive module explores the phases, checkpoints, and protein regulators of the cell cycle. The module also shows how mutations in genes that encode cell cycle regulators can lead to the development of cancer.

BCR-ABL: Protein Structure and Function

This tutorial describes the structure and function of the cancer-causing protein BCR-ABL. It also shows how drugs targeting this protein can help treat chronic myeloid leukemia (CML), a cancer of the white blood cells.

Mutations in Cancer

This video provides an overview of the types of genes that, when mutated, can lead to the development of cancer.