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Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness.

Cancer Cell Invasion

This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.

“Fixing” Gene Expression

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

Activity for Genes as Medicine

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

Living Together

This activity explores images of the bobtail squid, which serve as phenomena for learning about symbiosis and interspecies interactions.

Cell Division and Cancer Risk

This activity guides the analysis of a published scientific figure from a study that investigated how random mutations during cell division can contribute to cancer.

Sizing up the Brain Gene by Gene

In this talk, biomedical scientist Christopher Walsh discusses how DNA sequencing technology has led to a better understanding of the genes involved in brain development.

Cancer as a Genetic Disease

In this talk, biomedical scientist Charles Sawyers discusses how understanding the mutations that cause cancer can guide the development of targeted drug therapies.