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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this activity, students interpret several pedigrees of autosomal dominant and recessive conditions and consider the benefits and limitations of genetic testing.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

This interactive module introduces the anatomy of the immune system and walks through the timeline of a typical immune response.

The added information provided at pause points within the animation Coral Bleaching allows for a richer exploration of coral reefs, symbiosis, and other topics in biology.

This video case study explores the approaches scientists used to identify a mutation that causes retinitis pigmentosa (RP), a progressive disease that leads to blindness.

This activity guides the analysis of a published scientific figure from a study that explored the evolutionary origins of parasitic beetles that mimic army ants.

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.

This interactive module explores how CRISPR-Cas9 technology works and the many ways in which scientists are using it in their research.

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”