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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this activity, students interpret several pedigrees of autosomal dominant and recessive conditions and consider the benefits and limitations of genetic testing.

In this activity, wildfires and how much area they burn serve as a phenomenon to guide student inquiry, which includes evaluating data and developing scientific claims.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

This activity explores images of a coral bleaching event, which serve as phenomena for learning about marine ecosystems, human impacts, and climate change.

This activity explores content presented in the animated video Solving Crimes with the Necrobiome, which describes the microbial changes associated with decomposing corpses.

In this activity, students engage with an example from the Serengeti ecosystem to illustrate the exchange of nutrients between plants, animals, and the environment.

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.

This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.

This activity guides the analysis of a published scientific figure from a study that investigated how salt affects the electron transport chain.

This activity explores the content presented in the animated video Nature’s Cutest Symbiosis: The Bobtail Squid, which describes how the light produced by bacteria living inside bobtail squid helps the squid avoid its predators.

This activity explores the content presented in the animated film Termites Digest Wood Thanks to Microbes, which describes the symbiotic relationship between termites and the wood-digesting protists in their gut.