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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

This interactive module allows students and educators to build models that explain how the Earth system works. The Click & Learn can be used to show how Earth is affected by human activities and natural phenomena.

This activity guides the analysis of a published scientific figure from a study that investigated how random mutations during cell division can contribute to cancer.

This activity explores images of chalk formations and coccolithophores, which serve as phenomena for learning about the interactions between biological and geological processes.

A number of questions are embedded within the short film The Making of the Fittest: The Birth and Death of Genes, which illustrates how gene duplications and mutations have led to remarkable physiological adaptations in Antarctic fish.

This interactive module explores key human impacts on the environment and how they have affected Earth’s landscape, ocean, atmosphere, and biodiversity.

This activity reinforces concepts presented in the short film The Making of a Theory. Using a map of the Malay Archipelago and information about the animals found on different islands, students discover the Wallace Line: a sharp boundary that separates distinct Asian and Australian fauna.

This activity guides students through building a conceptual model of how carbon dioxide affects Earth’s climate.

This activity supports concepts covered in the film The Day the Mesozoic Died. Students will analyze geological evidence from 10 different sites around the world to predict the location of the asteroid impact that caused the mass extinction at the end of the Cretaceous Period.

This interactive module allows students to explore the science of Earth's deep history, from its formation 4.5 billion years ago to modern times.

This activity allows students to calculate the mass, size, and kinetic energy of an asteroid that struck Earth 66 million years ago, based on the total abundance of iridium in a sediment layer. It supports concepts presented in the short film The Day the Mesozoic Died.