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Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness.

Activity for Genes as Medicine

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

Genes as Medicine

This film describes the scientific principles and the research efforts involved in the development of a gene therapy for a congenital form of blindness, and how a young patient benefited from this medical breakthrough.

DNA Profiling Activity

This multipart activity is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensics labs around the world.

Understanding Variation in Human Skin Color

In this activity, students extend the concepts covered in the short film The Biology of Skin Color through the application of models and mathematical thinking to explain how genomic variation and human ancestry can explain differences in skin color, a polygenic trait.

Spreadsheet Tutorial 4: t-Test

In this activity, students explore different ways of calculating t-values and performing t-tests using built-in functions in Excel or Google Sheets. Students apply what they learned by plotting beak size measurements of Galapágos finches collected before and after a drought.

Spreadsheet Tutorial 5: Histogram

In this activity, students explore different ways of constructing a histogram using Excel or Google Sheets. Students apply what they learned by plotting beak size measurements of Galapágos finches before and after a drought.

The Teosinte Hypothesis

In this activity, students further explore the short film Popped Secret: The Mysterious Origin of Corn, by working through the mathematical concepts behind George Beadle’s claim that teosinte is the wild ancestor of maize.

Gorongosa's Water Cycle

This animation illustrates the main stages of the water cycle in Gorongosa National Park, an ecosystem that experiences both wet and dry seasons.

Sampling and Normal Distribution

This interactive simulation allows students to graph and analyze sample distributions taken from a normally distributed population.