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Activity for Genes as Medicine

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

Genes as Medicine

This film describes the scientific principles and the research efforts involved in the development of a gene therapy for a congenital form of blindness, and how a young patient benefited from this medical breakthrough.

Epidemiology of Nipah Virus

This activity complements the video Virus Hunter: Monitoring Nipah Virus in Bat Populations. Students explore cases of Nipah virus infection, analyze evidence, and make calculations and predictions based on data.

Viral Lysis and Budding

This activity outlines two demonstrations that model how enveloped and nonenveloped viruses are released from infected cells.

HIV Receptors and Co-receptors

This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.

Viral DNA Integration

In this hands-on activity, students model how a double-stranded DNA copy of the HIV genome is integrated into the host cell DNA.

HIV Protease Inhibitors

This demonstration models how the HIV protease enzyme functions and how its activity is blocked by a class of anti-HIV drugs.

HIV Reverse Transcription and AZT

This activity allows students to model how the anti-HIV drug AZT (azidothymidine) interferes with the process of viral replication.

DNA Profiling Activity

This multipart activity is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensics labs around the world.

Ebola: Disease Detectives

This hands-on activity allows students to analyze DNA sequences of Ebola viruses. Students use these sequences to track the virus’s spread during the 2013–2016 Ebola outbreak in West Africa.