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Sodium Channel Evolution in Electric Fish

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

Pelvic Evolution in Sticklebacks

This activity guides the analysis of a published scientific figure from a study that used SNP genotyping to identify the mutations that result in morphological differences in stickleback fish.

“Fixing” Gene Expression

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

Monkey Social Status and Immune Response

This activity guides the analysis of a published scientific figure from a study on how social status affects the expression of genes involved in immune system processes.

Stalking the Genetic Basis of a Trait

This activity supports the film Popped Secret: The Mysterious Origin of Corn. Students analyze data on the expression of the tb1 gene to explain how variations in this gene played a role in the evolution of corn.

Central Dogma and Genetic Medicine

This interactive module uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat different genetic conditions.

HIV Protease Inhibitors

This demonstration models how the HIV protease enzyme functions and how its activity is blocked by a class of anti-HIV drugs.

HIV Reverse Transcription and AZT

This activity allows students to model how the anti-HIV drug AZT (azidothymidine) interferes with the process of viral replication.

Zebrafish and Skin Color

In this activity, students explore how experimental work in zebrafish led to a better understanding of the role of the gene SLC24A5 in human skin color. The activity complements the film The Biology of Skin Color.

Written in Chalk

This activity explores images of chalk formations and coccolithophores, which serve as phenomena for learning about the interactions between biological and geological processes.

Interactive Assessment for Evolving Switches, Evolving Bodies

A number of interactive questions are embedded within the short film The Making of the Fittest: Evolving Switches, Evolving Bodies, which illustrates how mutations in gene regulatory regions can result in the evolution of major anatomical features.