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Sodium Channel Evolution in Electric Fish

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

Developing an Explanation for Tuskless Elephants

This activity builds on information presented in the video Selection for Tuskless Elephants. Students use scientific evidence and reasoning to construct an explanation of and develop an argument for tusklessness in elephant populations.

Cancer Cell Invasion

This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.

Cystic Fibrosis Mechanism and Treatment

This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop treatments for the disease.

Pelvic Evolution in Sticklebacks

This activity guides the analysis of a published scientific figure from a study that used SNP genotyping to identify the mutations that result in morphological differences in stickleback fish.

Using Images as Phenomena

This hands-on activity engages students in asking questions about phenomena using collections of images.

“Fixing” Gene Expression

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

Monkey Social Status and Immune Response

This activity guides the analysis of a published scientific figure from a study on how social status affects the expression of genes involved in immune system processes.

Activity for Genes as Medicine

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

The Search for a Mutated Gene

This video describes the case of a patient with retinitis pigmentosa (RP), a progressive disease that leads to blindness, and how physician-scientist Dr. Ed Stone approached the search for the causal mutation.