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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

This interactive module introduces the anatomy of the immune system and walks through the timeline of a typical immune response.

This activity guides the analysis of a published scientific figure from a study that investigated physiological and genetic adaptations in the Bajau, a group of people who traditionally do freediving.

This activity explores images of the bobtail squid, which serve as phenomena for learning about symbiosis and interspecies interactions.

This activity guides the analysis of a published scientific figure from a study that investigated how random mutations during cell division can contribute to cancer.

A number of questions are embedded within the short film The Making of the Fittest: The Birth and Death of Genes, which illustrates how gene duplications and mutations have led to remarkable physiological adaptations in Antarctic fish.

This interactive module explores the circulatory systems of major vertebrate groups to gain insights into their evolution.

This interactive module explores the phases, checkpoints, and protein regulators of the cell cycle. The module also shows how mutations in genes that encode cell cycle regulators can lead to the development of cancer.

This video provides an overview of the types of genes that, when mutated, can lead to the development of cancer.

This animation shows how the cancer treatment Gleevec inhibits the cancer-causing protein BCR-ABL.

This film explores how gene duplications and mutations have led to remarkable physiological adaptations in Antarctic fish.