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Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness.

Red Tattoo

This activity explores an image of tattoo ink particles inside cells, which serves as a phenomenon for learning about the structure and color of human skin.

Mozambique Mounds

This activity explores an image of termite mounds in the African savanna, which serves as a phenomenon for learning about ecosystems, competition, and feedback loops.

Mate Choice in Spiders

This activity guides the analysis of a published scientific figure from a study that investigated how males in a species of sexually cannibalistic spiders choose their mates.

Cancer Cell Invasion

This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.

Cystic Fibrosis Mechanism and Treatment

This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop treatments for the disease.

“Fixing” Gene Expression

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

Monkey Social Status and Immune Response

This activity guides the analysis of a published scientific figure from a study on how social status affects the expression of genes involved in immune system processes.

Activity for Genes as Medicine

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.