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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

This activity guides the analysis of a published scientific figure from a study that investigated physiological and genetic adaptations in the Bajau, a group of people who traditionally do freediving.

This activity guides the analysis of a published scientific figure from a study on how social status affects the expression of genes involved in immune system processes.

This activity explores images of the bobtail squid, which serve as phenomena for learning about symbiosis and interspecies interactions.

This activity analyzes a published scientific figure from a study assessing if the microbiota from a mother affects the immune systems of the developing offspring.

This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.

This activity explores images of chalk formations and coccolithophores, which serve as phenomena for learning about the interactions between biological and geological processes.

This activity reinforces concepts presented in the short film The Making of a Theory. Using a map of the Malay Archipelago and information about the animals found on different islands, students discover the Wallace Line: a sharp boundary that separates distinct Asian and Australian fauna.

This activity guides students through building a conceptual model of how carbon dioxide affects Earth’s climate.

This activity supports concepts covered in the film The Day the Mesozoic Died. Students will analyze geological evidence from 10 different sites around the world to predict the location of the asteroid impact that caused the mass extinction at the end of the Cretaceous Period.

This activity allows students to calculate the mass, size, and kinetic energy of an asteroid that struck Earth 66 million years ago, based on the total abundance of iridium in a sediment layer. It supports concepts presented in the short film The Day the Mesozoic Died.

This activity allows students to analyze the chemical data that led researchers to conclude that a layer of clay at the boundary between the Cretaceous and Paleogene rock layers (the K-Pg boundary) contained an extraordinary concentration of iridium. It supports concepts presented in the short film The Day the Mesozoic Died.