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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this activity, wildfires and how much area they burn serve as a phenomenon to guide student inquiry, which includes evaluating data and developing scientific claims.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

In this inquiry-based activity, students engage in science practices to figure out ways environmental factors drive the natural selection and adaptation of Galápagos finches.

This activity explores images of a coral bleaching event, which serve as phenomena for learning about marine ecosystems, human impacts, and climate change.

This activity explores content presented in the animated video Solving Crimes with the Necrobiome, which describes the microbial changes associated with decomposing corpses.

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

This activity explores images of planarians regenerating missing body parts, which serve as phenomena for learning about cell division and differentiation.

This activity guides the analysis of a published scientific figure from a study that investigated how salt affects the electron transport chain.

This activity explores the content presented in the animated video How Tube Worms Survive at Hydrothermal Vents, which tells the story of the symbiotic relationship between the giant tube worm and chemosynthetic bacteria.

This activity analyzes a published scientific figure from a study assessing if the microbiota from a mother affects the immune systems of the developing offspring.

This activity analyzes a published scientific figure from a study that investigated the biological importance of sleep. In this study, scientists tested whether sleep plays a role in removing harmful substances from the brain.