1 - 12 of 59 results
Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness.

Sodium Channel Evolution in Electric Fish

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

Cancer Cell Invasion

This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.

Sex Verification Testing of Athletes

This interactive module explores the biology of sex determination and development in humans, set against the backdrop of the different sex testing policies implemented throughout sports history.

Cystic Fibrosis Mechanism and Treatment

This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop treatments for the disease.

“Fixing” Gene Expression

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

Activity for Genes as Medicine

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

The Search for a Mutated Gene

This video describes the case of a patient with retinitis pigmentosa (RP), a progressive disease that leads to blindness, and how physician-scientist Dr. Ed Stone approached the search for the causal mutation.

Genes as Medicine

This film describes the scientific principles and the research efforts involved in the development of a gene therapy for a congenital form of blindness, and how a young patient benefited from this medical breakthrough.

Central Dogma and Genetic Medicine

This interactive module uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat different genetic conditions.

Sleep Clears β-amyloid from the Brain

This activity analyzes a published scientific figure from a study that investigated the biological importance of sleep. In this study, scientists tested whether sleep plays a role in removing harmful substances from the brain.