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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

In this inquiry-based activity, students engage in science practices to figure out ways environmental factors drive the natural selection and adaptation of Galápagos finches.

This activity explores the concepts and research presented in the short film Out of the Ashes: Dawn of the Age of Mammals, which explores how life on Earth recovered after a major asteroid impact.

This activity explores images of elephants with and without tusks, which serve as phenomena for learning about selection and human impacts on the frequency of traits within populations.

In this activity, students explore using CRISPR-Cas9 to knock out butterfly genes in order to determine their function.

In this activity, students analyze aspects of a scientific paper that investigates genes involved in the colors and patterns of butterfly wings.

In this hands-on activity, students build a paper model to explore how CRISPR-Cas9 is used to edit genes.

In this activity, students engage with an example from the Serengeti ecosystem to illustrate the exchange of nutrients between plants, animals, and the environment.

This activity explores images of anole lizards subjected to strong winds, which serve as phenomena for learning about natural selection and the impacts of extreme climate events.

This activity guides the analysis of a published scientific figure from a study that investigated how anole lizards may adapt to extremely cold temperatures.

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.