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This film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell disease.

In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

This activity guides the analysis of a published scientific figure from a study that investigated how human populations might adapt to milk consumption, both genetically and culturally. 

This activity explores an image of fossil footprints at Laetoli, which serves as a phenomenon for learning about fossil evidence and human evolution.

In this activity, students explore using CRISPR-Cas9 to knock out butterfly genes in order to determine their function.

This activity explores content presented in the animated video Solving Crimes with the Necrobiome, which describes the microbial changes associated with decomposing corpses.

In this activity, students analyze aspects of a scientific paper that investigates genes involved in the colors and patterns of butterfly wings.

In this hands-on activity, students build a paper model to explore how CRISPR-Cas9 is used to edit genes.

This video case study explores the approaches scientists used to identify a mutation that causes retinitis pigmentosa (RP), a progressive disease that leads to blindness.

In this activity, students engage with an example from the Serengeti ecosystem to illustrate the exchange of nutrients between plants, animals, and the environment.

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.