This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness.

This activity builds on information presented in the video Selection for Tuskless Elephants. Students use scientific evidence and reasoning to construct an explanation of and develop an argument for tusklessness in elephant populations.

This interactive module allows students and educators to build models that explain how the Earth system works. The Click & Learn can be used to show how Earth is affected by human activities and natural phenomena.

This activity allows students to formulate and analyze scientific questions.

This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.

This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop treatments for the disease.

This interactive module explores how CRISPR-Cas9 technology works and the many ways in which scientists are using it in their research.

This hands-on activity engages students in asking questions about phenomena using collections of images.

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

This video describes the case of a patient with retinitis pigmentosa (RP), a progressive disease that leads to blindness, and how physician-scientist Dr. Ed Stone approached the search for the causal mutation.

This film describes the scientific principles and the research efforts involved in the development of a gene therapy for a congenital form of blindness, and how a young patient benefited from this medical breakthrough.