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In this phenomenon-driven activity, students investigate how cells are signaled to make melanin and explain how mutations in melanin pathway proteins affect the coat color of various organisms.

This Click & Learn traces the flow of energy from the Sun all the way to cells within organisms. The embedded questions and calculations guide students’ understanding of how energy is distributed through a variety of ecosystems.

This interactive module introduces the anatomy of the immune system and walks through the timeline of a typical immune response.

The added information provided at pause points within the animation Coral Bleaching allows for a richer exploration of coral reefs, symbiosis, and other topics in biology.

In this activity, students explore using CRISPR-Cas9 to knock out butterfly genes in order to determine their function.

In this activity, students analyze aspects of a scientific paper that investigates genes involved in the colors and patterns of butterfly wings.

In this hands-on activity, students build a paper model to explore how CRISPR-Cas9 is used to edit genes.

This video case study explores the approaches scientists used to identify a mutation that causes retinitis pigmentosa (RP), a progressive disease that leads to blindness.

In this activity, students engage with an example from the Serengeti ecosystem to illustrate the exchange of nutrients between plants, animals, and the environment.

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.

This activity guides the analysis of a published scientific figure from a study that investigated physiological and genetic adaptations in the Bajau, a group of people who traditionally do freediving.