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Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness.

Red Tattoo

This activity explores an image of tattoo ink particles inside cells, which serves as a phenomenon for learning about the structure and color of human skin.

Coloration in Vertebrates

This activity explores images of animals with a mutation that affects coloration, which serve as phenomena for learning about skin color genetics and evolution.

Cancer Cell Invasion

This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.

Human Origins

This interactive module allows students to examine fossils of early humans and compare them to modern primates.

Cystic Fibrosis Mechanism and Treatment

This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop treatments for the disease.

“Fixing” Gene Expression

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

Tiktaalik Fossil: Skull

This model shows the skull of Tiktaalik, a vertebrate that existed about 375 million years ago and had features of both fish and tetrapods (four-limbed animals).

Tiktaalik Fossil: Body

This model shows the skeleton of Tiktaalik, a vertebrate that existed about 375 million years ago and had features of both fish and tetrapods (four-limbed animals).

Tiktaalik Fossil: Pectoral Fin

This model shows the pectoral fin bones of Tiktaalik, a vertebrate that existed about 375 million years ago and had features of both fish and tetrapods (four-limbed animals).

Tiktaalik Fossil: Pelvis

This model shows the pelvis of Tiktaalik, a vertebrate that existed about 375 million years ago and had features of both fish and tetrapods (four-limbed animals).