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Cancer as a Genetic Disease

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Topic

  • Genetics
  • Genetic Disease
  • Mutations

Duration

58 minutes 33 seconds
Archived
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Description

In this talk, biomedical scientist Charles Sawyers discusses how understanding the mutations that cause cancer can guide the development of targeted drug therapies.

Despite decades of research, cancer continues to be a major cause of death in the United States. Advances in cancer biology have led to the development of targeted drugs as new and effective treatment options for some types of cancer. Sawyers presents an overview of cancer biology and describes how understanding the molecular mechanisms involved in one type of cancer, chronic myeloid leukemia, resulted in the development of Gleevec, one of the first targeted cancer drugs.

This talk is from a 2013 Holiday Lecture Series, Medicine in the Genomic Era.

Key Terms

BCR-ABL, chronic myeloid leukemia (CML), dasatinib, Gleevec, health care, imatinib, medicine, mutation, oncogene, tumor suppressor gene

Terms of Use

Please see the Terms of Use for information on how this resource can be used.

Version History

Date Published 03.20.14

Materials

Video (MP4) 225 MB
Transcript (PDF) 346 KB
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