Teaching the Central Dogma Using the Rock Pocket Mouse and Genetic Medicine
This playlist can be used to teach several core topics in genetics and molecular biology related to the central dogma by connecting students with case studies about the rock pocket mouse and genetic medicine. The topics covered include the central dogma of molecular biology (gene expression), mutations, biotechnology, and genetic medicine approaches.
By completing the resources in this playlist, students will be able to:
- Describe the steps of eukaryotic gene expression.
- Identify types of mutations and determine their possible effects on the phenotype of an individual.
- Predict which steps of eukaryotic gene expression offer opportunities for interventions that can lead to the development of new therapeutics.
- Explain how CRISPR-Cas9 works and how it is used in research.
- Visualize molecular aspects of transcription and translation.
This playlist can be used in undergraduate biology courses. Implementing this playlist should take about 125 minutes of class time in total, spread out among other discussions and activities.