Teaching Genetics and Molecular Biology Using Lactose Intolerance
This playlist can be used to teach several core concepts in genetics and molecular biology by having students collect and interpret evidence to explain the biology of lactose intolerance. The topics covered include enzyme and carbohydrate biochemistry, the molecular basis of inheritance, and the regulation of gene expression. The activities provide several opportunities for students to collect and analyze data, including a wet lab.
By completing the resources in this playlist, students will be able to:
- Design a controlled experiment to test for enzyme activity.
- Describe how enzymes catalyze only specific chemical reactions.
- Determine the inheritance pattern of a trait from a pedigree.
- Use the central dogma of biology to explain the molecular mechanisms by which mutations can affect protein production.
- Give examples of how gene expression can be regulated at different points in the process.
This playlist can be used in a general high school biology course. Implementing this playlist should take about eight to nine 50-minute class periods.
Visit the Storyline Viewer to see the storyline (“Genetics of Lactose Intolerance”) using this resource sequence.