Classroom Resources

This film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell disease.

In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
 

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

This interactive module uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat different genetic conditions.

This interactive module explores how mutations arise in germline and somatic cells. It also shows how these mutations can lead to genetic conditions, such as cystic fibrosis and cancer.

This activity guides the analysis of a published scientific figure from a study that used SNP genotyping to identify genes involved in autism.