Classroom Resources

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

This activity guides the analysis of a published scientific figure from a study that investigated how random mutations during cell division can contribute to cancer.

This activity analyzes a published scientific figure from a study of a family that has a high prevalence of Alzheimer’s disease.

This activity guides the analysis of a published scientific figure from a study that used SNP genotyping to identify genes involved in autism.

This activity guides the analysis of a published scientific figure from a study that tested a new treatment for chronic myeloid leukemia (CML), a cancer of white blood cells.

This interactive module explores the phases, checkpoints, and protein regulators of the cell cycle. The module also shows how mutations in genes that encode cell cycle regulators can lead to the development of cancer.

These two hands-on activities engage students in exploring the genetic basis of cancer using cards and posters.