1 - 12 of 115 results
Inheritance and Mutations in a Single-Gene Disorder

This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.

Biochemistry & Molecular Biology
Genetics
Lessons
High School — General
High School — AP/IB
College
Skin Color and Human Evolution

This activity guides the analysis of a published scientific figure from a study that investigated genetic factors contributing to skin color differences, particularly within African populations.

Genetics
Evolution
Science Practices
Data Points
High School — General
High School — AP/IB
College
Sodium Channel Evolution in Electric Fish

This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.

Genetics
Anatomy & Physiology
Evolution
Science Practices
Data Points
High School — General
High School — AP/IB
College
Cancer Cell Invasion

This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.

Genetics
Cell Biology
Phenomenal Images
High School — General
High School — AP/IB
Cystic Fibrosis Mechanism and Treatment

This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop treatments for the disease.

Biochemistry & Molecular Biology
Genetics
Cell Biology
Animations
High School — General
High School — AP/IB
College
CRISPR-Cas9 Mechanism & Applications

This interactive module explores how CRISPR-Cas9 technology works and the many ways in which scientists are using it in their research.

Biochemistry & Molecular Biology
Genetics
Click & Learn
High School — General
High School — AP/IB
College
Pelvic Evolution in Sticklebacks

This activity guides the analysis of a published scientific figure from a study that used SNP genotyping to identify the mutations that result in morphological differences in stickleback fish.

Genetics
Evolution
Science Practices
Data Points
High School — General
High School — AP/IB
College
“Fixing” Gene Expression

In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

Biochemistry & Molecular Biology
Genetics
Card Activities
High School — General
High School — AP/IB
College
Monkey Social Status and Immune Response

This activity guides the analysis of a published scientific figure from a study on how social status affects the expression of genes involved in immune system processes.

Genetics
Anatomy & Physiology
Science Practices
Data Points
High School — General
High School — AP/IB
College
Activity for Genes as Medicine

This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

Biochemistry & Molecular Biology
Genetics
Film Activities
High School — General
High School — AP/IB
College
The Search for a Mutated Gene

This video describes the case of a patient with retinitis pigmentosa (RP), a progressive disease that leads to blindness, and how physician-scientist Dr. Ed Stone approached the search for the causal mutation.

Biochemistry & Molecular Biology
Genetics
Scientists at Work
High School — General
High School — AP/IB
College
Genes as Medicine

This film describes the scientific principles and the research efforts involved in the development of a gene therapy for a congenital form of blindness, and how a young patient benefited from this medical breakthrough.

Biochemistry & Molecular Biology
Genetics
Short Films
High School — General
High School — AP/IB
College