In this inquiry-based activity, students engage in science practices to figure out why some people with a genetic condition that usually leads to sickle cell disease do not have disease symptoms.
This video presents an intriguing phenomenon: two patients who carry the same genetic variation, which is known to cause sickle cell disease, have very different outcomes.
In this inquiry-based activity, students investigate the phenomenon of fur colors in rock pocket mice to connect genotypes to phenotypes and molecular genetics to evolution.
This activity explores images of stickleback fish, some with spines and some without spines, which serve as phenomena for learning about gene regulation and natural selection.
This video case study explores the approaches scientists used to identify a mutation that causes retinitis pigmentosa (RP), a progressive disease that leads to blindness.
This activity builds on information presented in the short film Genes as Medicine. Students interpret actual pedigrees to determine the inheritance pattern of Leber congenital amaurosis (LCA), an inherited form of blindness. They also examine protein sequence data to explore mutations that can cause LCA.
This activity guides the analysis of a published scientific figure from a study that investigated genetic factors contributing to skin color differences, particularly within African populations.
This activity guides the analysis of a published scientific figure from a study that investigated how gene duplication contributed to the evolution of electric fish.
This activity explores an image of tumor cells invading muscle tissue, which serves as a phenomenon for learning about cancer, mutations, and cell division.
This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop treatments for the disease.
