Skip to main content
HHMI BioInteractive
  • Español
  • Site Search
  • Log in
  • Create Account
  • Community
    • Group Rules
    • Join the Community
  • Classroom Resources
  • Teaching Tools
  • Professional Development
  • Partner Content

Structure of Dengue Virus

Topic

  • Biochemistry & Molecular Biology
  • Macromolecules
  • Microbiology
  • Viruses
  • Pathogens & Disease

Resource Type

  • Videos
  • Animations

Level

High School — AP/IBCollege

Duration

00:01:03
Saved By
3 Users
Share This

Description

This animation zooms into a 3D model of dengue virus, moving from the virus’s outer structures to its inner core.

As shown in the animation, the outside of the dengue virus is made up of glycoproteins arranged in geometric patterns of two-, three-, and five-fold symmetry. These glycoproteins float over a lipid bilayer that covers the nucleocapsid, a protein core encasing the virus’s RNA genome.

This animation is a clip from a 2010 Holiday Lecture Series, Viral Outbreak: The Science of Emerging Disease. Depending on students’ background, it may be helpful to pause the animation at various points to discuss different parts of the viral structure.

Key Terms

capsid, envelope, glycoprotein, infectious disease, lipid, protein, RNA genome

Primary Literature

Kuhn, R. J., Wei Zhang, Michael G. Rossmann, Sergei V. Pletnev, Jeroen Corver, Edith Lenches, Christopher T. Jones, et al. “Structure of Dengue Virus: Implications for Flavivirus Organization, Maturation, and Fusion.” Cell 108, 5 (2002): 717–725. https://doi.org/10.1016/S0092-8674(02)00660-8. ​​​​​​

Terms of Use

Please see the Terms of Use for information on how this resource can be used.

Accessibility Level (WCAG compliance)

Video files meet criteria.

Version History

Date Published 02.05.10

Materials

Download Large (MOV) 8 MB
Download Large (WMV) 8 MB
Download Small (MOV) 5 MB
Download Small (WMV) 5 MB
Download Transcript (PDF) 11 KB

Use This Resource With

Interactive Media Resource
Interactive Video Builder

Explore Related Content

Other Related Resources

Showing of
Computer image of three different viruses
Animations
Viral Geometry and Structural Diversity
Computer illustration of viruses infecting a cell
Animations
Recombination of Viral Genomes
Image from the video
Animations
Treating HIV Infection with Protease Inhibitors
Image from the interactive
Click & Learn
Stopping Mosquito-Borne Disease
3D model of the Ebola virus
Click & Learn
Virus Explorer
Computer illustration of viruses
Animations
Viral Life Cycle
Volunteers hand out masks and hand sanitizer at a public event.
Scientists at Work
COVID-19 Sparks Community Action
Image from the film of researchers feeding a fruit bat
Scientists at Work
Virus Hunter: Monitoring Nipah Virus in Bat Populations
Image from the activity
Data Points
Patterns of Zoonotic Disease
Image of a slide from the video
Clips
Relative Sizes of Bacteria and Viruses
HHMI BioInteractive
  • About Us
  • Our Team
  • Our Advisors
  • FAQ
  • Contact Us
  • Facebook
  • Instagram
  • Twitter
  • YouTube
  • Newsletter Signup
  • HHMI.org
  • Terms of Use
  • Privacy Policy
  • Accessibility