Stalking the Genetic Basis of a Trait
Description
Student Learning Targets
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Analyze amino acid and DNA sequences to determine that differences in the coding region of tb1 are not the cause of phenotypic differences between corn and teosinte but are evidence of a close evolutionary relationship.
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Construct an explanation based on evidence for how the structure of DNA in a regulatory region determines the expression of proteins that further affect the expression of other genes.
Estimated Time
Key Terms
corn, gene expression, gene regulation, Hopscotch insertion, maize, mutation, phenotype, regulatory region, tb1 gene, teosinte
Primary Literature
Studer, Anthony, Qiong Zhao, Jeffrey Ross-Ibarra, and John Doebley. “Identification of a functional transposon insertion in the maize domestication gene tb1.” Nature Genetics 43, 11, (2011): 1160–1163. https://doi.org/10.1038/ng.942.
Studer, Anthony J., Huai Wang, and John F. Doebley. “Selection during maize domestication targeted a gene network controlling plant and inflorescence architecture.” Genetics 207, 2 (2017): 755–765. https://doi.org/10.1534/genetics.117.300071.
Terms of Use
The resource is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license. No rights are granted to use HHMI’s or BioInteractive’s names or logos independent from this Resource or in any derivative works.
Accessibility Level (WCAG compliance)
Version History
NGSS (2013)
HS-LS1-1, HS-LS3-1, HS-LS4-1; SEP1, SEP4, SEP6
AP Biology (2019)
EVO-1.N, IST-1.J, IST-1.K, IST-1.N, IST-1.P, IST-2.A, IST-2.B, IST-2.C, IST-2.D, IST-4.B; SP1, SP3, SP4, SP6
IB Biology (2016)
3.1, 3.4, 7.2
IB Environmental Systems and Societies (2017)
3.2
Common Core (2010)
ELA.RST.9–12.7, ELA.WHST.9–12.1
Vision and Change (2009)
CC1, CC3; DP1
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